Biological Networks

It is well established that bacteria engage in social behavior and form networked communities via molecular signaling. We analyze the network dynamics and biofilm metrics, showing that our method can effectively reveal the underlying intercellular communication process and community organization within the biofilm. We claim that the application of social and network sciences to understanding bacteria population dynamics can aid in developing better drugs to control the many pathogenic bacteria that use social interactions to cause infections.

biological networks

Selected Publications

19 entries « 3 of 4 »

Bogdan, Paul; Deasy, Bridget M; Gharaibeh, Burhan; Roehrs, Timo; Marculescu, Radu

Heterogeneous structure of stem cells dynamics: statistical models and quantitative predictions Journal Article

In: Scientific reports, 4 , pp. 4826, 2014.

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Zhuang, Jiang; Wei, Guopeng; Carlsen, Rika Wright; Edwards, Matthew R; Marculescu, Radu; Bogdan, Paul; Sitti, Metin

Analytical modeling and experimental characterization of chemotaxis in serratia marcescens Journal Article

In: Physical Review E, 89 (5), pp. 52704, 2014.

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Wei, Guopeng; Marculescu, Radu

Don't Let History Repeat Itself: Optimal Multidrug Quorum Quenching of Pathogens Network Inproceedings

In: Proceedings of ACM The First Annual International Conference on Nanoscale Computing and Communication, pp. 1–9, 2014.

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Wei, Guopeng; Marculescu, Radu

Miniature devices in the wild: Modeling molecular communication in complex extracellular spaces Journal Article

In: IEEE Journal on Selected Areas in Communications, 32 (12), pp. 2344–2353, 2014.

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Wei, Guopeng; Bogdan, Paul; Marculescu, Radu

Bumpy rides: Modeling the dynamics of chemotactic interacting bacteria Journal Article

In: IEEE Journal on Selected Areas in Communications, 31 (12), pp. 879–890, 2013.

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Wei, Guopeng; Bogdan, Paul; Marculescu, Radu

Efficient modeling and simulation of bacteria-based nanonetworks with BNSim Journal Article

In: IEEE Journal on Selected Areas in Communications, 31 (12), pp. 868–878, 2013.

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19 entries « 3 of 4 »